AbstractrnrnThe Industrial Revolution 4.0 is a new technological advancement that integrates thernphysical, digital and biological world, where there is a fundamental change in the human’srnway of life. With the rapid development of technology that has experienced breakthroughs inrnall disciplines, including in the field of artifical intelligence, nanotechnology, biotechnology,rninternet-based technology has an impact on human life that can increase the economicrngrowth too. The impact of economic growth has increased in the 4.0 industrial revolutionrnwhere this can be seen from many business people and entrepreneurs who utilize therninformation technology, so that the basic principles of industrial design 4.0 are known as therndigital revolution because of the proliferation of computers and automation and connectivityrnin a field. With the Industrial Revolution 4.0, there is an increasing influence in therneconomic sector, where the sector opens opportunities for entrepreneurship and MSMEsrnincrease rapidly, thus giving an impact on entrepreneurship for economic independence. Keywords: Industrial Revolution 4.0, Entrepreneurship, Economic Independence,ComputerrnPoliferation, Artificiall intelligent